Urticarial vasculitis diascopy in dermatology

Urticarial vasculitis (UV), a subtype of leukocytoclastic vasculitis, is a small vessel necrotizing vasculitis characterized by urticarial lesions and decreased serum complement. Primarily a disease of adult women, this immune complex disorder is seldom reported in children. Skin biopsy may be performed to confirm urticarial vasculitis. Microscopic findings of early lesions include a neutrophil leukocytoclastic vasculitis, in which there is damage to small vessels in the middle layers of the skin (dermis). In later lesions, a lymphocytic vasculitis may be seen. Introduction. Urticarial vasculitis is an eruption of erythematous wheals that clinically resemble urticaria, but differ in that lesions persist for greater than 24 hours, often demonstrate purpura, and histologically show changes of leukocytoclastic vasculitis. Urticarial vasculitis may be divided into normocomplementaemic.

Urticarial vasculitis diascopy in dermatology

Most patients are eventually diagnosed with chronic idiopathic urticaria. IgG autoantibody to IgE receptor or IgE itself causes urticarial lesions in 30% of these patients. Only a minority (approximately 10%) of patients with chronic urticarial lesions have urticarial vasculitis. Urticarial vasculitis (UV) is a small vessel vasculitis and an immune-complex mediated disease like other leukocytoclastic vasculitis. UV seems similar to common urticaria clinically. Major difference between urticarial vasculitis and urticaria is the duration of lesions. Urticarial lesions regress in 24 hours, but UV lesions persist longer than 24 hours. U rticarial vasculitis is a clinicopathological condition characterized by persistent urticarial weals, which on histology show features of a vasculitis (venulitis). It is frequently accompanied with systemic involvement. The variety of cutaneous, systemic, and serological features has resulted in different nomenclature in the earlier literature, including hypocomplementemia with cutaneous.

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Vasculitis - An Overview, time: 14:31
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