Urticarial vasculitis diascopy in dermatology
Urticarial vasculitis (UV), a subtype of leukocytoclastic vasculitis, is a small vessel necrotizing vasculitis characterized by urticarial lesions and decreased serum complement. Primarily a disease of adult women, this immune complex disorder is seldom reported in children. Skin biopsy may be performed to confirm urticarial vasculitis. Microscopic findings of early lesions include a neutrophil leukocytoclastic vasculitis, in which there is damage to small vessels in the middle layers of the skin (dermis). In later lesions, a lymphocytic vasculitis may be seen. Introduction. Urticarial vasculitis is an eruption of erythematous wheals that clinically resemble urticaria, but differ in that lesions persist for greater than 24 hours, often demonstrate purpura, and histologically show changes of leukocytoclastic vasculitis. Urticarial vasculitis may be divided into normocomplementaemic.